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CEP104 Polyclonal Antibody
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Product Details
BS-12283R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CEP104, amino acids 265-540.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The KIAA0562 gene product has been provisionally designated KIAA0562 pending further characterization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centrosomal protein 104kDa; Centrosomal protein of 104 kDa; Cep104; Gly-, L-Glu and TCP-binding protein; Glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein; glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein; likely ortholog of H. sapiens glycine-, glutamate-, thienylcyclohexylpiperidine-binding protein; unnamed protein product
Gene Aliases: A930027E11; AI115523; CEP104; CFAP256; GlyBP; JBTS25; KIAA0562; mKIAA0562; MRT77; ROC22
UniProt ID: (Human) O60308, (Rat) D3Z8X7, (Mouse) Q80V31
Entrez Gene ID: (Human) 9731, (Rat) 246295, (Mouse) 230967
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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