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Invitrogen
CEP290 Polyclonal Antibody
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FIGURE: 1 / 2
CEP290 Antibody (PA5-39088) in WB
Western blot was performed using Anti-CEP290 Polyclonal Antibody (Product # PA5-39088) and a 290 kDa band corresponding to CEP290 was observed in only Mouse Spleen and not in other tissues which are reported to be low to negative for its expression. Tissue extracts (40 µg lysate) of Mouse Spleen (Lane 1), Mouse Heart (Lane 2) and Mouse Lung (Lane 3) were electrophoresed using NuPAGE™ 3-8% Tris-Acetate Protein Gels (Product # EA0378BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 D... View More
Product Details
PA5-39088
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide derived from the internal region of human CEP290
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
Target Information
This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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