CERK has 2 isoforms with the molecular weight of 60 and 38 kDa.
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 ).
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Protein Aliases: Acylsphingosine kinase; Ceramide kinase; CERK antibody; hCERK; Lipid kinase 4; lipid kinase LK4; LK4; mCERK
Gene Aliases: AI848610; CERK; D330016D08Rik; dA59H18.2; dA59H18.3; hCERK; KIAA1646; LK4; mKIAA1646
Molecular Function: kinase