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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 85 and 335 of Human CERK|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29306 targets CERK in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29306 immunogen is recombinant fragment corresponding to a region within amino acids 85 and 335 of Human CERK.
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Acylsphingosine kinase; Ceramide kinase; dA59H18.2; dA59H18.3; hCERK; Lipid kinase 4; lipid kinase LK4; LK4
CERK; dA59H18.2; dA59H18.3; hCERK; KIAA1646; LK4