Recommended positive controls: H1299, HeLa, HepG2, Raji.
Predicted reactivity: Mouse (88%), Rat (90%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 ).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acylsphingosine kinase; Ceramide kinase; CERK antibody; hCERK; Lipid kinase 4; lipid kinase LK4; LK4
Gene Aliases: CERK; dA59H18.2; dA59H18.3; hCERK; KIAA1646; LK4
UniProt ID: (Human) Q8TCT0
Entrez Gene ID: (Human) 64781
Molecular Function: kinase