Recommended positive controls: HepG2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Carboxylesterase 2; carboxylesterase 2 (intestine, liver); CE-2; CES-2; Cocaine esterase; hCE-2; intestinal carboxylesterase; liver carboxylesterase-2; Methylumbelliferyl-acetate deacetylase 2; P iCE
Gene Aliases: CE-2; CES2; CES2A1; ICE; PCE-2
UniProt ID: (Human) O00748
Entrez Gene ID: (Human) 8824
Molecular Function: esterase