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Proteintech
CETP Polyclonal Antibody
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Product Details
13459-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CETP Fusion Protein Ag3923 (144-493 aa encoded by BC025739)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TQLTCDSGR VRTDAPDCYL SFHKLLLHLQ GEREPGWIKQ LFTNFISFTL KLVLKGQICK EINVISNIMA DFVQTRAASI LSDGDIGVDI SLTGDPVITA SYLESHHKGH FIYKNVSEDL PLPTFSPTLL GDSRMLYFWF SERVFHSLAK VAFQDGRLML SLMGDEFKAV LETWGFNTNQ EIFQEVVGGF PSQAQVTVHC LKMPKISCQN KGVVVNSSVM VKFLFPRPDQ QHSVAYTFEE DIVTTVQASY SKKKLFLSLL DFQITPKTVS NLTESSSESI QSFLQSMITA VGIPEVMSRL EVVFTALMNS KGVSLFDIIN PEIITRDGFL LLQMDFGFPE HLLVDFLQSL S (144-493 aa encoded by BC025739)
Target Information
It has been proposed that high density lipoproteins (HDLs) function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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