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OriGene
HDAC10 Monoclonal Antibody (OTI2H6), TrueMAB™
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Product Details
CF500760
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI2H6
Immunogen
Full length human recombinant protein of human HDAC10 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced; dJ402G11.7; DKFZp761B039; HD10; HDAC10b; Histone deacetylase 10; MGC149722; Polyamine deacetylase HDAC10; related to Hda1; RP3-402G11.7
Gene Aliases: HD10; HDAC10
UniProt ID: (Human) Q969S8
Entrez Gene ID: (Human) 83933
negative regulation of transcription from RNA polymerase II promoter
DNA repair
DNA recombination
chromatin organization
regulation of transcription, DNA-templated
autophagy
cellular response to DNA damage stimulus
macroautophagy
positive regulation of mismatch repair
reciprocal DNA recombination
negative regulation of transcription, DNA-templated
macromolecule deacylation
polyamine deacetylation
spermidine deacetylation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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