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          • Primary Antibodies ›
          • CBX8 Antibodies

          OriGene

          CBX8 Monoclonal Antibody (OTI3A11), TrueMAB™

          View all (13) CBX8 antibodies

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          Cite CBX8 Monoclonal Antibody (OTI3A11), TrueMAB™

          Additional Information:
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          • Antibody Testing Data (3)
          CBX8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CBX8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          CBX8 Antibody (CF800492) in IHC (P)

          Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CBX8 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA800492) {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CBX8 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CBX8 Antibody in Western Blot (WB)
          CBX8 Antibody in Western Blot (WB)
          CBX8 Monoclonal Antibody (OTI3A11), TrueMAB™

          Product Details

          CF800492

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:150
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG2b

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI3A11

          Immunogen

          Human recombinant protein fragment corresponding to amino acids 1-260 of human CBX8 produced in E.coli.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • Biotin 
          • Request custom conjugation

          Form

          Lyophilized

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 8% trehalose

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

          Target Information

          Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: chromobox homolog 8 (Pc class homolog, Drosophila); Chromobox protein homolog 8; HPC3; Pc class 3 homolog; Pc3; PC3; similar to polycomb; polycomb 3; Polycomb 3 homolog; polycomb group protein; Rectachrome 1; unnamed protein product

          View more View less

          Gene Aliases: CBX8; PC3; RC1

          View more View less

          UniProt ID: (Human) Q9HC52

          View more View less

          Entrez Gene ID: (Human) 57332

          View more View less

          Function(s)
          chromatin binding single-stranded RNA binding protein binding H3K27me3 modified histone binding ubiquitin-protein transferase activator activity
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter chromatin organization positive regulation of cell proliferation positive regulation of collagen biosynthetic process positive regulation of DNA repair cellular response to hydrogen peroxide
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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