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Reconstitute at 0.2 mg/mL in sterile PBS.
This gene is a member of the complement factor H (CFH) gene family, and encodes one of the 5 CFH-related (CFHR) proteins. These 5 genes are closely linked to the CFH gene on chromosome 1q31-q32. The CFHRs are secreted plasma proteins synthesized primarily by the hepatocytes, and composed of highly-related short consensus repeats (SCRs). This protein enhances the cofactor activity of CFH, and is involved in complement regulation. It can associate with lipoproteins and may play a role in lipid metabolism. Alternatively spliced transcript variants encoding different isoforms (varying in the number of SCRs) have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: complement factor H; Complement factor H-related protein 4; FHR-4; unnamed protein product
Gene Aliases: CFHL4; CFHR4; FHR-4; FHR4
UniProt ID: (Human) Q92496
Entrez Gene ID: (Human) 10877
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