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CGA Antibody (PA5-106875) in ICC/IF
Immunocytochemistry analysis of CGA in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with CGA polyclonal antibody (Product # PA5-106875) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-106875
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CGA(Accession P01215), corresponding to amino acid residues Q37-K87.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854539
Product Specific Information
Antibody detects endogenous levels of total CGA.
Target Information
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Anterior pituitary glycoprotein hormones common subunit alpha; CG-alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; chorionic gonadotropin human; chorionic gonadotropin, alpha polypeptide; Follicle-stimulating hormone alpha chain; follicle-stimulating hormone alpha subunit; Follitropin alpha chain; FSH-alpha; Glycoprotein hormones alpha chain; glycoprotein hormones, alpha subunit; human chorionic gonadotropin; LSH-alpha; Luteinizing hormone alpha chain; Lutropin alpha chain; pituitary hormone alpha subunit; Thyroid-stimulating hormone alpha chain; Thyrotropin alpha chain; TSH-alpha
Gene Aliases: aGSU; alpha-GSU; alphaGSU; alphaSU; CG-ALPHA; CGA; Cga1; FSHA; GPHa; GPHA1; GPHalpha; HCG; LHA; TSHA
UniProt ID: (Human) P01215, (Mouse) P11963, (Rat) P11962
Entrez Gene ID: (Human) 1081, (Mouse) 12640, (Rat) 116700
signal transduction
cell-cell signaling
positive regulation of cell proliferation
peptide hormone processing
positive regulation of cell migration
positive regulation of transcription from RNA polymerase II promoter
thyroid hormone generation
gonad development
thyroid gland development
luteinizing hormone secretion
cellular response to hormone stimulus
negative regulation of organ growth
follicle-stimulating hormone secretion
developmental growth
biological_process
Performance Guarantee
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