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Invitrogen
CHCHD2 Polyclonal Antibody
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FIGURE: 1 / 4
CHCHD2 Antibody (PA5-99995) in IHC (P)
Immunohistochemistry analysis of CHCHD2 in rat brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with CHCHD2 polyclonal antibody (Product # PA5-99995) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99995
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHCHD2(Accession Q9Y6H1), corresponding to amino acid residues P40-A90.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CHCHD2.
Target Information
Transcription factor. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 16.7kD protein; AAG10; Aging-associated gene 10 protein; Coiled-coil-helix-coiled-coil-helix domain-containing protein 2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial; ethanol induced 6; HCV NS2 trans-regulated protein; mitochondria nuclear retrograde regulator 1; mitochondrial nuclear retrograde regulator 1; MIX17 homolog B; NS2TP
Gene Aliases: AAG10; AL033347; C7orf17; CHCHD2; Etohi6; MIX17B; MNRR1; NS2TP; PARK22
UniProt ID: (Human) Q9Y6H1, (Mouse) Q9D1L0
Entrez Gene ID: (Human) 51142, (Mouse) 14004, (Rat) 316643
positive regulation of transcription from RNA polymerase II promoter
regulation of cellular response to hypoxia
mitochondrion organization
cellular response to oxidative stress
regulation of generation of precursor metabolites and energy
positive regulation of mitochondrial ATP synthesis coupled electron transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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