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A suggested positive control is rat liver tissue lysate.
PA5-34487 can be used with blocking peptide PEP-1529.
CHCHD7 is a newly identified member of a multifamily of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain. Northern blot analysis revealed that the gene is ubiquitously expressed. Its biological function is unknown and the gene has hitherto not been associated with neoplasia. CHCHD7 and PLAG1 are located head-to-head about 500 bp apart in 8q12. A chromosomal aberration involving CHCHD7 is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland.
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Protein Aliases: coiled-coil-helix-coiled-coil-helix domain containing 7; Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; COX23 cytochrome c oxidase assembly homolog
Gene Aliases: 1810049H20Rik; CHCHD7; COX23
UniProt ID: (Human) Q9BUK0, (Mouse) Q8K2Q5
Entrez Gene ID: (Human) 79145, (Mouse) 66433, (Rat) 684258
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