This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
Recommended positive controls: 293T, HepG2, HepG2 nucleus.
Predicted reactivity: Mouse (92%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1; MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amplified in liver cancer 1; Amplified in liver cancer protein 1; chromodomain helicase DNA binding protein 1-like; Chromodomain-helicase-DNA-binding protein 1-like
Gene Aliases: ALC1; CHD1L; CHDL
UniProt ID: (Human) Q86WJ1
Entrez Gene ID: (Human) 9557