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Invitrogen
CHD2 Polyclonal Antibody
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FIGURE: 1 / 3
CHD2 Antibody (PA5-79039) in IHC (P)
Immunohistochemical analysis of CHD2 in paraffin-embedded section of mouse brain tissue . Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-CHD2 antibody (Product # PA5-79039) overnight at 4°C. Biotinylated goat anti-rabbit IgG was use... View More
Product Details
PA5-79039
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human CHD2 recombinant protein (Position: R1124-K1351).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: monkey COS-7 whole cell, human Siha whole cell, rat brain tissue, rat C6 whole cell, mouse brain tissue, mouse NIH/3T3 whole cell. IHC: rat brain tissue, mouse brain tissue.
Target Information
The CHD family of proteins is characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent chromatin remodeler CHD2; ATP-dependent helicase CHD2; CHD-2; Chromo domain-containing protein 2; chromodomain-helicase-DNA-binding protein 2; DKFZp547I1315; DKFZp686E01200; DKFZp781D1727; FLJ38614; unnamed protein product
Gene Aliases: 2810013C04Rik; 2810040A01Rik; 5630401D06Rik; AI851092; BC029703; CHD-2; CHD2; DEE94; EEOC
UniProt ID: (Human) O14647, (Mouse) E9PZM4
Entrez Gene ID: (Human) 1106, (Rat) 308738, (Mouse) 244059
nucleotide binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
chromatin binding
RNA binding
protein binding
ATP binding
hydrolase activity
ATPase activity
histone binding
ATP-dependent chromatin remodeler activity
core promoter sequence-specific DNA binding
helicase activity
poly(A) RNA binding
cellular response to DNA damage stimulus
muscle organ development
metabolic process
hematopoietic stem cell differentiation
chromatin organization
chromatin remodeling
gene expression
nucleosome organization
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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