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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2 or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family. The CHD family of proteins are ATP-dependent chromatin remodeling enzymes which combine chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability. Localized to the cytoplasm and the nucleus, CHD9 contains two chromodomains, one ATPbinding helicase domain and one C-terminal helicase domain. Chromodomains are protein regions of about 40-50 amino acid residues found in proteins associated with chromatin remodeling and manipulation. The domain is highly conserved among both plants and animals and is found in a large variety of proteins from many genomes. CHD9 acts as a transcriptional coactivator for PPARα and may also be an ATP-dependent chromatin remodeling protein. CHD9 is widely expressed at low levels and is present as three isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent helicase CHD9; BC022889; CHD-9; chromatin remodeling factor CHROM1; Chromatin-related mesenchymal modulator; Chromatin-remodeling factor CHROM1; Chromodomain-helicase-DNA-binding protein 9; ciprofibrate bound protein p240; ciprofibrate-bound protein PRIC320; CReMM; FLJ12178; Kismet homolog 2; Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein; PPAR-alpha-interacting complex protein 320 kDa; PPAR{gamma}-interacting cofactor 320 kDa; proteinx0008
Gene Aliases: 1810014J18Rik; 9030205D12Rik; A330063D19Rik; AD-013; AD013; CHD-9; CHD9; CReMM; KIAA0308; KISH2; mKIAA0308; PRIC320; x0008
UniProt ID: (Human) Q3L8U1, (Mouse) Q8BYH8
Entrez Gene ID: (Human) 80205, (Mouse) 109151
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