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Product Details
PA5-26401
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CHIA
Conjugate
Unconjugated
Form
Liquid
Concentration
0.29 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2543901
Target Information
CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acidic chitinase; Acidic mammalian chitinase; AMCase; Lung-specific protein TSA1902; YNL
Gene Aliases: 2200003E03Rik; AMCASE; CHIA; Chia1; CHIT2; TSA1902; YNL
UniProt ID: (Human) Q9BZP6, (Mouse) Q91XA9
Entrez Gene ID: (Human) 27159, (Mouse) 81600
Molecular Function:
glycosidase
polysaccharide catabolic process
production of molecular mediator involved in inflammatory response
carbohydrate metabolic process
chitin metabolic process
chitin catabolic process
cell wall chitin metabolic process
apoptotic process
immune response
digestion
response to fungus
positive regulation of chemokine secretion
immune system process
inflammatory response
metabolic process
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