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Invitrogen
CHML Polyclonal Antibody
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FIGURE: 1 / 2
CHML Antibody (PA5-101802) in ICC/IF
Immunofluorescent analysis of CHML in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with CHML polyclonal antibody (Product # PA5-101802) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-101802
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHML(Accession P26374), corresponding to amino acid residues V127-E177.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CHML.
Target Information
Binds unprenylated Rab proteins, presents it to the catalytic component B, and remains bound to it after the geranylgeranyl transfer reaction. The component A may be regenerated by transferring its prenylated Rab to a protein acceptor. Less effective than REP-1 in supporting prenylation of Rab3 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: choroideraemia-like protein; choroideremia-like (Rab escort protein 2); Choroideremia-like protein; Rab escort protein 2; rab escort protein-2; Rab proteins geranylgeranyltransferase component A 2; REP-2
Gene Aliases: AI450814; CHML; E030003F13Rik; REP-2; REP2
UniProt ID: (Human) P26374, (Mouse) Q9QZD5
Entrez Gene ID: (Human) 1122, (Mouse) 12663
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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