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Product Details
PA5-114255
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal region of Mouse Chmp4c
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2884769
Product Specific Information
Immunogen sequence: SEAFSQRVQF ADGFDEAELL AELEELEQEE LNKKMTSLEL PNVPSSSLPA
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 92%
Target Information
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Charged multivesicular body protein 4c; CHMP4c; chromatin modifying protein 4C; Chromatin-modifying protein 4c; Snf7 homologue associated with Alix 3
Gene Aliases: 2010012P02Rik; 2210015K02Rik; 2310010I16Rik; Chmp4c; Shax3; Snf7-3
UniProt ID: (Mouse) Q9D7F7
Entrez Gene ID: (Mouse) 66371
cell separation after cytokinesis
transport
nucleus organization
vacuolar transport
mitotic metaphase plate congression
bioluminescence
abscission
regulation of centrosome duplication
protein transport
negative regulation of cytokinesis
regulation of viral process
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of viral release from host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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