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          • Primary Antibodies ›
          • CHMP5 Antibodies

          Invitrogen

          CHMP5 Polyclonal Antibody

          View all (13) CHMP5 antibodies

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          Cite CHMP5 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          CHMP5 Antibody in Western Blot (WB)
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          CHMP5 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          CHMP5 Antibody (PA5-18365) in WB

          Western blot analysis of CHMP5 using CHMP5 Polyclonal Antibody (Product # PA5-18365) (x µg/mL) in staining of K562 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CHMP5 Antibody in Western Blot (WB)
          CHMP5 Polyclonal Antibody

          Product Details

          PA5-18365

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-3 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide sequence (NKDGVLVDEFGLPQ) corresponding to the C-terminus amino acids of CHMP5 (aa 202-216).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Amount

          100 µg

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          TBS, pH 7.3, with 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10976825

          Product Specific Information

          This antibody is predicted to react with bovine, mouse and rat based on sequence homology.

          This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

          Target Information

          CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III, a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: apoptosis-related protein PNAS-2; Charged multivesicular body protein 5; Chromatin-modifying protein 5; HGNC:26942; hVps60; small protein with inherent killing effect; SNF7 domain containing 2; SNF7 domain-containing protein 2; unnamed protein product; Vacuolar protein sorting-associated protein 60; Vps60

          View more View less

          Gene Aliases: C9orf83; CGI-34; CHMP5; HSPC177; PNAS-114; PNAS-2; SNF7DC2; Spike; Vps60

          View more View less

          UniProt ID: (Human) Q9NZZ3

          View more View less

          Entrez Gene ID: (Human) 51510

          View more View less

          Function(s)
          protein binding cadherin binding
          Process(es)
          plasma membrane repair regulation of receptor recycling membrane budding autophagy nucleus organization vacuolar transport lysosome organization mitotic metaphase plate congression endosome to lysosome transport regulation of centrosome duplication protein transport erythrocyte differentiation nuclear envelope reassembly late endosome to vacuole transport via multivesicular body sorting pathway multivesicular body assembly viral budding via host ESCRT complex ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway viral budding viral budding from plasma membrane vesicle fusion with vacuole multivesicular body-lysosome fusion midbody abscission cellular response to lipopolysaccharide cellular response to muramyl dipeptide multivesicular body sorting pathway membrane fission autophagosome maturation regulation of mitotic spindle assembly late endosome to lysosome transport ESCRT III complex disassembly
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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