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Invitrogen
CHMP5 Polyclonal Antibody
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FIGURE: 1 / 5
CHMP5 Antibody (PA5-21787) in ICC/IF
CHMP5 Polyclonal Antibody detects CHMP5 protein at cytoplasm by immunofluorescent analysis. Sample: HL-60 cells were fixed in ice-cold MeOH for 5 min. Green: CHMP5 protein stained by CHMP5 Polyclonal Antibody (Product # PA5-21787) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-21787
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CHMP5. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse stomach.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (92%), Pig (100%), Chicken (94%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III, a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies. Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apoptosis-related protein PNAS-2; Charged multivesicular body protein 5; chromatin modifying protein 5; Chromatin-modifying protein 5; HGNC:26942; hVps60; likely ortholog of H. sapiens SNF7 domain containing 2; SNF7 domain containing 2; SNF7 domain-containing protein 2; Vacuolar protein sorting-associated protein 60; Vps60
Gene Aliases: 2210412K09Rik; AW545668; C9orf83; CGI-34; CHMP5; HSPC177; PNAS-114; PNAS-2; SNF7DC2; Vps60
UniProt ID: (Human) Q9NZZ3, (Mouse) Q9D7S9
Entrez Gene ID: (Human) 51510, (Mouse) 76959
cell separation after cytokinesis
regulation of receptor recycling
nucleus organization
lysosome organization
mitotic metaphase plate congression
endosome to lysosome transport
regulation of centrosome duplication
protein transport
endosomal transport
viral life cycle
multivesicular body assembly
viral budding
multivesicular body sorting pathway
cell-cell adhesion
regulation of mitotic spindle assembly
ESCRT III complex disassembly
transport
vacuolar transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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