Immunogen sequence: KAYKQVKIDQ IEDLQDQLED MMEDANEIQE ALSRSYGTPE LDEDDLEAEL D
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein family. These proteins are components of ESCRT-III , a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies . Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A , is required for both MVB formation and regulation of cell cycle progression .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis-related protein PNAS-2; C9orf83; CGI-34; Charged multivesicular body protein 5; chromatin modifying protein 5; Chromatin-modifying protein 5; HSPC177; hVps60; PNAS-2; SNF7 domain containing 2; SNF7 domain-containing protein 2; SNF7DC2; Vacuolar protein sorting-associated protein 60; Vps60
Gene Aliases: C9orf83; CGI-34; CHMP5; HSPC177; PNAS-114; PNAS-2; SNF7DC2; Vps60
UniProt ID: (Human) Q9NZZ3
Entrez Gene ID: (Human) 51510
Molecular Function: transfer/carrier protein