Recommended positive controls: HeLa, HepG2, mouse liver, rat liver.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (94%), Chicken (96%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcineurin B homolog; Calcineurin B homologous protein 1; Calcineurin B-like protein; calcineurin homologous protein; calcineurin-like EF hand protein 1; calcineurin-like EF-hand protein 1; calcium binding protein P22; Calcium-binding protein CHP; Calcium-binding protein p22; EF-hand Ca2+-binding protein p22; EF-hand calcium-binding domain-containing protein p22; p24; Sid 470; SLC9A1 binding protein
Gene Aliases: 1500003O03Rik; AA960066; AI046351; Cahp; CHP; CHP1; p22; p24; Sid470; Sid470p; SLC9A1BP; vac; Wrch2