Sequence of this protein is as follows: MGGMKYIFSL LFFLLLEGGK TEQVKHSETY CMFQDKKYRV GERWHPYLEP YGLVYCVNCI CSENGNVLCS RVRCPNVHCL SPVHIPHLCC PRCPDSLPPV NNKVTSKSCE YNGTTYQHGE LFVAEGLFQN RQPNQCTQCS CSEGNVYCGL KTCPKLTCAF PVSVPDSCCR VCRGDGELSW EHSDGDIFRQ PANREARHSY HRSHYDPPPS RQAGGLSRFP GARSHRGALM DSQQASGTIV QIVINNKHKH GQVCVSNGKT YSHGESWHPN LRAFGIVECV LCTCNVTKQE CKKIHCPNRY PCKYPQKIDG KCCKVCPGKK AKELPGQSFD NKGYFCGEET MPVYESVFME DGETTRKIAL ETERPPQVEV HVWTIRKGIL QHFHIEKISK RMFEELPHFK LVTRTTLSQW KIFTEGEAQI SQMCSSRVCR TELEDLVKVL YLERSEKGHC
CHRDL1 is an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.
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Protein Aliases: chordin-like 1; Chordin-like protein 1; neuralin 1; Neuralin-1; Neurogenesin-1; Ventroptin; ventroptin-alpha; ventroptin-beta
Gene Aliases: CHL; CHL1; CHRDL1; dA141H5.1; MGC1; MGCN; Ng1; NRLN1; VOPT