Invitrogen

CHRDL1 Polyclonal Antibody

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CHRDL1 Antibody in Western Blot (WB) — Western blot analysis of CHRDL1 in rat tissue extract using 50 µg of protein. Samples were separated with 10% SDS-PAGE and incubated with CHRDL1 polyclonal antibody (Product # PA5-78591) using a dilution of 1:500.

CHRDL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of CHRDL1 in paraffin-embedded mouse hind brain. Sample was incubated with CHRDL1 polyclonal antibody (Product # PA5-78591) using a dilution of 1:500.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:3000

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human CHRDL1. The exact sequence is proprietary.

Conjugate

Unconjugated

Form

Liquid

Concentration

0.84 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2735641

Product Specific Information

Positive Control: rat brain

Predicted Reactivity: Human (100%), Chicken (82%), Rhesus Monkey (100%)

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

CHRDL1 is an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: chordin-like 1; Chordin-like protein 1; Kohjirin; neuralin 1; Neuralin-1; neurogenesin 1; Neurogenesin-1; Ventroptin; ventroptin-alpha; ventroptin-beta

Gene Aliases: CHL; CHL1; CHRDL1; dA141H5.1; Kjr; MGC1; MGCN; Neurogenesin-1; Ng1; NRLN1; VOPT

UniProt ID: (Human) Q9BU40, (Mouse) Q920C1, (Rat) Q76LD0

Entrez Gene ID: (Human) 91851, (Mouse) 83453, (Rat) 363455

Molecular Function: cell adhesion molecule extracellular matrix glycoprotein extracellular matrix protein