This antibody is predicted to react with canine, mouse and rat based on sequence homology.
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor; AChR M1; cholinergic receptor; M1 mAChR; m1 muscarinic acetylcholine receptor protein; MGC30125; Muscarinic acetylcholine receptor M1
Gene Aliases: Chrm-1; Chrm1; M1; M1R
UniProt ID: (Mouse) P12657
Entrez Gene ID: (Mouse) 12669
Molecular Function: G-protein coupled receptor