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Proteintech
CHRM3 Polyclonal Antibody
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Product Details
21978-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHRM3 fusion protein Ag17791
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RTKELAGLQA SGTEAETENF VHPTGSSRSC SSYELQQQSM KRSNRRKYGR CHFWFTTKSW KPSSEQMDQD HSSSDSWNNN DAAASLENSA SSDEEDIGSE TRAIYSIVLK LPGHSTILNS TKLPSSDNLQ VPEEELGMVD LERKADKLQA QKSVDDGGSF PKSFSKLPIQ LESAVDTAKT SDVNSSVGKS TATLPLSFKE ATLAKRFALK TRSQITK
Target Information
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 3; AChR M3; cholinergic receptor; cholinergic receptor, muscarinic 3, cardiac; cytotransmitter gated ion channel; G protein coupled receptor; m3 muscarinic receptor; Mm3 mAChR; muscarinic acetylcholine receptor 3; Muscarinic acetylcholine receptor M3
Gene Aliases: Chrm-3; CHRM3; EGBRS; HM3; M3; m3AChR; M3R; PBS
UniProt ID: (Human) P20309, (Mouse) Q9ERZ3, (Rat) P08483
Entrez Gene ID: (Human) 1131, (Mouse) 12671, (Rat) 24260
smooth muscle contraction
regulation of smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
G-protein coupled acetylcholine receptor signaling pathway
chemical synaptic transmission
synaptic transmission, cholinergic
nervous system development
calcium-mediated signaling
positive regulation of insulin secretion
protein modification process
positive regulation of smooth muscle contraction
saliva secretion
acetylcholine receptor signaling pathway
ligand-gated ion channel signaling pathway
regulation of vascular smooth muscle contraction
digestion
sensory perception of chemical stimulus
regulation of vasoconstriction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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