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Invitrogen
CHRNA5 Polyclonal Antibody
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Product Details
PA5-102470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHRNA5(Accession P30532), corresponding to amino acid residues E203-Y253.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CHRNA5.
Target Information
Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor alpha 5; acetylcholine receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor; Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5; cholinergic receptor, nicotinic alpha 5; cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; nAChR alpha 5; Neuronal acetylcholine receptor subunit alpha-5; neuronal nicotinic acetylcholine receptor, alpha5 subunit; nicotinic acetylcholine receptor alpha5 subunit
Gene Aliases: Acra-5; Acra5; CHRNA5; LNCR2; NACHRA5
UniProt ID: (Human) P30532, (Mouse) Q2MKA5
Entrez Gene ID: (Human) 1138, (Mouse) 110835, (Rat) 25102
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
protein binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine-gated cation channel activity
acetylcholine-activated cation-selective channel activity
acetylcholine binding
protein heterodimerization activity
ligand-gated ion channel
ion transport
signal transduction
chemical synaptic transmission
synaptic transmission, cholinergic
neuromuscular synaptic transmission
ion transmembrane transport
response to nicotine
behavioral response to nicotine
membrane depolarization
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
acetylcholine receptor signaling pathway
presynaptic modulation of chemical synaptic transmission
transport
cation transport
cation transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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