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          • Primary Antibodies ›
          • CHRNB1 Antibodies

          Proteintech

          CHRNB1 Polyclonal Antibody

          6 References
          View all (8) CHRNB1 antibodies

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          Cite CHRNB1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          CHRNB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          CHRNB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          CHRNB1 Antibody (11553-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human colon cancer using 11553-1-AP (CHRNB1 antibody) at dilution of 1:50 (under 10x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CHRNB1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CHRNB1 Antibody in Western Blot (WB)
          CHRNB1 Antibody in Western Blot (WB)
          CHRNB1 Antibody in Immunoprecipitation (IP)
          CHRNB1 Polyclonal Antibody

          Product Details

          11553-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 6 publications 6 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          CHRNB1 Fusion Protein Ag2108 (151-501 aa encoded by BC023553)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.4 mg/mL

          Amount

          60 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: CSIQVTYFP FDWQNCTMVF SSYSYDSSEV SLQTGLGPDG QGHQEIHIHE GTFIENGQWE IIHKPSRLIQ PPGDPRGGRE GQRQEVIFYL IIRRKPLFYL VNVIAPCILI TLLAIFVFYL PPDAGEKMGL SIFALLTLTV FLLLLADKVP ETSLSVPIII KYLMFTMVLV TFSVILSVVV LNLHHRSPHT HQMPLWVRQI FIHKLPLYLR LKRPKPERDL MPEPPHCSSP GSGWGRGTDE YFIRKPPSDF LFPKPNRFQP ELSAPDLRRF IDGPNRAVAL LPELREVVSS ISYIARQLQE QEDHDALKED WQFVAMVVDR LFLWTFIIFT SVGTLVIFLD ATYHLPPPDP FP (151-501 aa encoded by BC023553)

          Target Information

          The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: acetylcholine receptor; Acetylcholine receptor beta; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); AChR beta; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 1; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); Chrnb 1; nAChRB1; unnamed protein product

          View more View less

          Gene Aliases: Achr-2; ACHRB; Acrb; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; RNACRB1; SCCMS

          View more View less

          UniProt ID: (Human) P11230, (Rat) P25109, (Mouse) P09690

          View more View less

          Entrez Gene ID: (Human) 1140, (Rat) 24261, (Mouse) 11443

          View more View less

          Function(s)
          transmembrane signaling receptor activity ion channel activity extracellular ligand-gated ion channel activity protein binding channel activity ligand-gated ion channel activity acetylcholine receptor activity acetylcholine-gated cation channel activity acetylcholine binding transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential acetylcholine-activated cation-selective channel activity ligand-gated ion channel
          Process(es)
          postsynaptic membrane organization skeletal muscle contraction ion transport cation transport muscle contraction signal transduction synaptic transmission, cholinergic neuromuscular synaptic transmission ion transmembrane transport behavioral response to nicotine regulation of membrane potential neurological system process membrane depolarization muscle cell development regulation of postsynaptic membrane potential excitatory postsynaptic potential acetylcholine receptor signaling pathway muscle fiber development transmembrane transport cation transmembrane transport transport
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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