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Invitrogen
CHRNB1 Polyclonal Antibody
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Product Details
PA5-101398
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHRNB1(Accession P11230), corresponding to amino acid residues L63-V113.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CHRNB1.
Target Information
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetylcholine receptor; Acetylcholine receptor beta; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); AChR beta; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 1; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); Chrnb 1; nAChRB1; unnamed protein product
Gene Aliases: Achr-2; ACHRB; Acrb; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; RNACRB1; SCCMS
UniProt ID: (Human) P11230, (Rat) P25109, (Mouse) P09690
Entrez Gene ID: (Human) 1140, (Rat) 24261, (Mouse) 11443
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
protein binding
channel activity
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine-gated cation channel activity
acetylcholine binding
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
acetylcholine-activated cation-selective channel activity
ligand-gated ion channel
postsynaptic membrane organization
skeletal muscle contraction
ion transport
cation transport
muscle contraction
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
ion transmembrane transport
behavioral response to nicotine
regulation of membrane potential
neurological system process
membrane depolarization
muscle cell development
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
acetylcholine receptor signaling pathway
muscle fiber development
transmembrane transport
cation transmembrane transport
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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