Search
Invitrogen
CHRNB2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-29792
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human AChR beta 2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Amount
65 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (95%), Chicken (98%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor beta 2 neural; acetylcholine receptor, nicotinic, beta 2 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; Neuronal acetylcholine receptor subunit beta-2; neuronal nicotinic acetylcholine receptor beta 2; unnamed protein product
Gene Aliases: [b]2-nAchR; Acrb-2; Acrb2; C030030P04Rik; CHRNB2; EFNL3; nAChRB2
UniProt ID: (Human) P17787, (Rat) P12390, (Mouse) Q9ERK7
Entrez Gene ID: (Human) 1141, (Rat) 54239, (Mouse) 11444
transmembrane signaling receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
protein binding
ligand-gated ion channel activity
acetylcholine receptor activity
acetylcholine-gated cation channel activity
acetylcholine binding
acetylcholine-activated cation-selective channel activity
drug binding
protein heterodimerization activity
ligand-gated ion channel
response to hypoxia
ion transport
calcium ion transport
smooth muscle contraction
signal transduction
chemical synaptic transmission
synaptic transmission, cholinergic
visual perception
sensory perception of sound
learning
memory
locomotory behavior
associative learning
visual learning
regulation of dopamine secretion
sensory perception of pain
vestibulocochlear nerve development
optic nerve morphogenesis
lateral geniculate nucleus development
central nervous system projection neuron axonogenesis
positive regulation of B cell proliferation
regulation of synaptic transmission, dopaminergic
positive regulation of dopamine secretion
ion transmembrane transport
response to nicotine
behavioral response to nicotine
social behavior
regulation of dopamine metabolic process
B cell activation
response to cocaine
regulation of circadian sleep/wake cycle, REM sleep
response to ethanol
negative regulation of action potential
regulation of dendrite morphogenesis
neurological system process
cognition
membrane depolarization
regulation of synapse assembly
regulation of postsynaptic membrane potential
excitatory postsynaptic potential
synaptic transmission involved in micturition
acetylcholine receptor signaling pathway
response to acetylcholine
action potential
conditioned taste aversion
central nervous system neuron axonogenesis
positive regulation of synaptic transmission, dopaminergic
regulation of membrane potential
regulation of circadian sleep/wake cycle, non-REM sleep
protein heterooligomerization
cation transmembrane transport
transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support