Peptide sequence: LTLGLLAALA VCGSWGLNEE ERLIRHLFQE KGYNKELRPV AHKEESVDVA
Sequence homology: Cow: 91%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Pig: 100%; Rabbit: 86%; Rat: 85%; Zebrafish: 78%
The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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Protein Aliases: acetylcholine receptor; Acetylcholine receptor subunit delta; acetylcholine receptor, nicotinic, delta (muscle); cholinergic receptor; cholinergic receptor, nicotinic delta; cholinergic receptor, nicotinic, delta (muscle); cholinergic receptor, nicotinic, delta polypeptide
Gene Aliases: ACHRD; CHRND; CMS2A; CMS3A; CMS3B; CMS3C; FCCMS; SCCMS
UniProt ID: (Human) Q07001
Entrez Gene ID: (Human) 1144