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Invitrogen
CHST11 Polyclonal Antibody
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FIGURE: 1 / 1
CHST11 Antibody (PA5-89396) in WB
Western blot analysis of CHST11 in extracts of various cell lines. Samples were incubated with CHST11 Polyclonal antibody (Product # PA5-89396) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-89396
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 38-352 of human CHST11 (NP_0608831)
Conjugate
Form
Liquid
Concentration
0.52 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HPVMRRNPFG VDICCRKGSR SPLQELYNPI QLELSNTAVL HQMRRDQVTD TCRANSATSR KRRVLTPNDL KHLVVDEDHE LIYCYVPKVA CTNWKRLMMV LTGRGKYSDP MEIPANEAHV SANLKTLNQY SIPEINHRLK SYMKFLFVRE PFERLVSAYR NKFTQKYNIS FHKRYGTKII KRQRKNATQE ALRKGDDVKF EEFVAYLIDP HTQREEPFNE HWQTVYSLCH PCHIHYDLVG KYETLEEDSN YVLQLAGVGS YLKFPTYAKS TRTTDEMTTE FFQNISSEHQ TQLYEVYKLD FLMFNYSVPS YLKLE; Positive Samples: Raji, Rat brain; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
Target Information
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C4S-1; C4ST; C4ST-1; Carbohydrate sulfotransferase 11; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; IgH/CHST11 fusion
Gene Aliases: C4ST; C4ST-1; C4ST1; CHST11; HSA269537
UniProt ID: (Human) Q9NPF2, (Rat) P69478
Entrez Gene ID: (Human) 50515, (Rat) 314694
chondrocyte development
respiratory gaseous exchange
post-embryonic development
carbohydrate biosynthetic process
chondroitin sulfate biosynthetic process
negative regulation of transforming growth factor beta receptor signaling pathway
polysaccharide localization
post-anal tail morphogenesis
regulation of cell proliferation
embryonic digit morphogenesis
negative regulation of apoptotic process
developmental growth
embryonic viscerocranium morphogenesis
chondroitin sulfate metabolic process
embryonic limb morphogenesis
embryonic skeletal system morphogenesis
cartilage development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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