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CHST12 Polyclonal Antibody

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Antibody Testing Data (4)

CHST12 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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CHST12 Antibody (15341-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human colon cancer using 15341-1-AP (CHST12 antibody) at dilution of 1:50 (under 40x lens).

Product Image Gallery

CHST12 Antibody in Western Blot (WB) — K-562 cells were subjected to SDS PAGE followed by western blot with 15341-1-AP (CHST12 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Product Details

15341-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CHST12 Fusion Protein Ag7544 (64-414 aa encoded by BC002918)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

Immunogen sequence: SDVDEFLDK FLSAGVKQSD LPRKETEQPP APGSMEESVR GYDWSPRDAR RSPDQGRQQA ERRSVLRGFC ANSSLAFPTK ERAFDDIPNS ELSHLIVDDR HGAIYCYVPK VACTNWKRVM IVLSGSLLHR GAPYRDPLRI PREHVHNASA HLTFNKFWRR YGKLSRHLMK VKLKKYTKFL FVRDPFVRLI SAFRSKFELE NEEFYRKFAV PMLRLYANHT SLPASAREAF RAGLKVSFAN FIQYLLDPHT EKLAPFNEHW RQVYRLCHPC QIDYDFVGKL ETLDEDAAQL LQLLQVDRQL RFPPSYRNRT ASSWEEDWFA KIPLAWRQQL YKLYEADFVL FGYPKPENLL RD (64-414 aa encoded by BC002918)

Target Information

Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Nano-elemental selenium particle developed via supramolecular self-assembly of chondroitin sulfate A and Na₂SeO₃ to repair cartilage lesions.

Carbohydrate polymers

Han J,Deng H,Li Y,Qiao L,Jia H,Zhang L,Wang L,Qu C

Fri Sep 15 00:00:00 EDT 2023

Nano-elemental selenium particle developed via supramolecular self-assembly of chondroitin sulfate A and Na₂SeO₃ to repair cartilage lesions.

Carbohydrate polymers

Han J,Deng H,Li Y,Qiao L,Jia H,Zhang L,Wang L,Qu C

Fri Sep 15 00:00:00 EDT 2023

Abnormal expression of chondroitin sulfate sulfotransferases in the articular cartilage of pediatric patients with Kashin-Beck disease.

Histochemistry and cell biology

Lei J,Yan S,Zhou Y,Wang L,Zhang J,Guo X,Lammi MJ,Han J,Qu C

Sun Mar 01 00:00:00 EST 2020

Serious Selenium Deficiency in the Serum of Patients with Kashin-Beck Disease and the Effect of Nano-Selenium on Their Chondrocytes.

Biological trace element research

Wang L,Yin J,Yang B,Qu C,Lei J,Han J,Guo X

Sun Mar 01 00:00:00 EST 2020

Decreased Expression of CHST-12, CHST-13, and UST in the Proximal Interphalangeal Joint Cartilage of School-Age Children with Kashin-Beck Disease: an Endemic Osteoarthritis in China Caused by Selenium Deficiency.

Biological trace element research

Guo Y,Zhou Y,Yan S,Qu C,Wang L,Guo X,Han J

Tue Oct 01 00:00:00 EDT 2019

Biological trace element research

Guo Y,Zhou Y,Yan S,Qu C,Wang L,Guo X,Han J

Tue Oct 01 00:00:00 EDT 2019

The effects of long-term low selenium diet on the expression of CHST-3, CHST-12 and UST in knee cartilage of growing rats.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Wang L,Guo X,Yi J,Qu C,Lei J,Guo Q,Han J

Sat Dec 01 00:00:00 EST 2018

Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease.

Osteoarthritis and cartilage

Han J,Li D,Qu C,Wang D,Wang L,Guo X,Lammi MJ

Tue Aug 01 00:00:00 EDT 2017

Altered expression of chondroitin sulfate structure modifying sulfotransferases in the articular cartilage from adult osteoarthritis and Kashin-Beck disease.

Osteoarthritis and cartilage

Han J,Li D,Qu C,Wang D,Wang L,Guo X,Lammi MJ

Tue Aug 01 00:00:00 EDT 2017

Bioinformatics

Protein Aliases: C4ST-2; Carbohydrate sulfotransferase 12; Chondroitin 4-O-sulfotransferase 2; Chondroitin 4-sulfotransferase 2; Sulfotransferase Hlo

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Gene Aliases: AI595374; C4S-2; C4ST-2; C4ST2; CHST12; UNQ500/PRO1017

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UniProt ID: (Human) Q9NRB3, (Mouse) Q99LL3

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Entrez Gene ID: (Human) 55501, (Mouse) 59031, (Rat) 304322

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Molecular Function: transferase metabolite interconversion enzyme

Function(s)

carbohydrate biosynthetic process chondroitin sulfate biosynthetic process dermatan sulfate biosynthetic process carbohydrate metabolic process

Process(es)

chondroitin 4-sulfotransferase activity 3'-phosphoadenosine 5'-phosphosulfate binding sulfotransferase activity transferase activity

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CHST12 Polyclonal Antibody

CHST12 Antibody (15341-1-AP) in IHC (P)

Product Details

15341-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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