Immunogen sequence: VGKLETLDED AAQLLQLLQV DRQLRFPPSY RNRTASSWEE DWFAKIPLAW RQQLYKLYEA DFVLFGYPKP ENLLRD
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Activity toward partially desulfated dermatan sulfate is however lower. Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C4ST-2; Carbohydrate sulfotransferase 12; Chondroitin 4-O-sulfotransferase 2; Chondroitin 4-sulfotransferase 2; Sulfotransferase Hlo
Gene Aliases: C4S-2; C4ST-2; C4ST2; CHST12; UNQ500/PRO1017
UniProt ID: (Human) Q9NRB3
Entrez Gene ID: (Human) 55501
Molecular Function: transferase