Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Predicted to react with Mouse and Rat samples.
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: carbohydrate (dermatan 4) sulfotransferase 14; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14; Carbohydrate sulfotransferase 14; D4ST-1; dermatan 4 sulfotransferase 1; Dermatan 4-sulfotransferase 1; dermatan-4-sulfotransferase-1; hD4ST1
Gene Aliases: 2600016L03Rik; ATCS; CHST14; D4ST-1; D4ST1; EDSMC1; HNK1ST; UNQ1925/PRO4400
UniProt ID: (Human) Q8NCH0, (Mouse) Q80V53
Entrez Gene ID: (Human) 113189, (Mouse) 72136, (Rat) 691394
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support