Immunogen sequence: TSRMYEFVGL EFLPHLQTWV HNITRGKGMG DHAFHTNARD ALNVSQAWRW SLPYEKVSRL QKACGDAMNL LGYRHVRSEQ EQRNLLLDLL STWTVPEQIH
This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.
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Protein Aliases: carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4; Carbohydrate sulfotransferase 4; galactose/N-acetylglucosamine/N-acetylgalactosamine 6-O-sulfotransferase 3; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; GlcNAc6ST-2; gn6st-2; GST-3; HEC-GLCNAC-6-ST; HEC-GlcNAc6ST; High endothelial cells N-acetylglucosamine 6-O-sulfotransferase; L-selectin ligand sulfotransferase; LSST; N-acetylglucosamine 6-O-sulfotransferase 2
Gene Aliases: CHST4; GlcNAc6ST2; GST3; HECGLCNAC6ST; LSST
UniProt ID: (Human) Q8NCG5
Entrez Gene ID: (Human) 10164