PA5-31763 targets CHST7 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31763 immunogen is recombinant fragment corresponding to a region within amino acids 86 and 323 of Human CHST7.
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This gene belongs to the sulfotransferase gene family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes. This gene is part of a gene cluster on chromosome Xp11.23.
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Protein Aliases: C6ST-2; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7; Carbohydrate sulfotransferase 7; Chondroitin 6-sulfotransferase 2; chondroitin 6-sulfotransferase-2; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5; GlcNAc6ST-4; gn6st-4; GST-5; N-acetylglucosamine 6-O-sulfotransferase 4
Gene Aliases: C6ST-2; CHST7; GST-5
UniProt ID: (Human) Q9NS84
Entrez Gene ID: (Human) 56548