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Product Details
PA5-43412
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human CHST8
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2605466
Product Specific Information
Peptide sequence: GCSNWKRVLM VLAGLASSTA DIQHNTVHYG SALKRLDTFD RQGILHRLST
Sequence homology: Cow: 86%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%
Target Information
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the Golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; Carbohydrate sulfotransferase 8; GalNAc-4-O-sulfotransferase 1; GALNAC-4-ST1; galNAc4ST-1; N-acetylgalactosamine-4-O-sulfotransferase 1
Gene Aliases: CHST8; GalNAc4ST; GALNAC4ST1; PSS3
UniProt ID: (Human) Q9H2A9
Entrez Gene ID: (Human) 64377
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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