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Product Details
21848-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:200-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
CHT1 Fusion Protein Ag16136 (457-580 aa encoded by BC111525) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.46 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: QPLIFYPGY YPDDNGIYNQ KFPFKTLAMV TSFLTNICIS YLAKYLFESG TLPPKLDVFD AVVARHSEEN MDKTILVKNE NIKLDELALV KPRQSMTLSS TFTNKEAFLD VDSSPEGSGT EDNLQ (457-580 aa encoded by BC111525)
Target Information
Acetylcholine functions as a neurotransmitter in both the central and peripheral nervous systems of all vertebates, and is the principle neurotransmitter used at the neuromuscular junction. Presynaptic synthesis of acetylcholine requires a steady supply of choline, which is acquired by a plasma membrane high affinity choline transporter (CHT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CHT; hCHT; Hemicholinium-3-sensitive choline transporter; High affinity choline transporter 1; high affinity choline transporter; hemicholinium-3-sensitive choline transporter; MGC126299; MGC126300; solute carrier family 5 (choline transporter), member 7; solute carrier family 5 (sodium/choline cotransporter), member 7; Solute carrier family 5 member 7; solute carrier family 5, member 7
Gene Aliases: CHT; CHT1; HMN7A; SLC5A7
UniProt ID: (Human) Q9GZV3, (Mouse) Q8BGY9, (Rat) Q9JMD7
Entrez Gene ID: (Human) 60482, (Mouse) 63993, (Rat) 85426
Molecular Function:
transporter
sodium ion transport
neurotransmitter secretion
synaptic transmission, cholinergic
neuromuscular synaptic transmission
acetylcholine biosynthetic process
choline transport
transmembrane transport
transport
ion transport
organic cation transport
sodium ion transmembrane transport
neurotransmitter biosynthetic process
ammonium transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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