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Invitrogen
CHX10 Polyclonal Antibody
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Product Details
PA5-82092
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human VSX2. Recombinant protein control fragment (Product #RP-89128).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LGLNKEPPSS HPRAALDGLA PGHLLAARSV LSPAGVGGMG LLGPGGLPGF YTQPTFLEVL SDPQSVHLQP LGRASGPLDT SQTASSDSED VSSSDRKMSK SALNQTKKRK KRRHRTIFTS YQLEELEKAF NEAH
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 99%.
Target Information
CHX10 encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ceh-10 homeo domain containing homolog; Ceh-10 homeodomain-containing homolog; homeobox protein; Homeobox protein CHX10; Visual system homeobox 2
Gene Aliases: CHX10; HOX10; MCOP2; MCOPCB3; RET1; VSX2
UniProt ID: (Human) P58304
Entrez Gene ID: (Human) 338917, (Rat) 171360
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
sequence-specific double-stranded DNA binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
neuroblast proliferation
negative regulation of neuroblast proliferation
visual perception
cell proliferation
positive regulation of cell proliferation
central nervous system neuron differentiation
camera-type eye development
cell fate commitment
positive regulation of transcription from RNA polymerase II promoter
retinal bipolar neuron differentiation
retina morphogenesis in camera-type eye
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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