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This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
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Protein Aliases: Capicua; Protein capicua homolog
Gene Aliases: 1200010B10Rik; CIC; KIAA0306; mKIAA0306
UniProt ID: (Human) Q96RK0, (Mouse) Q6PDJ8
Entrez Gene ID: (Human) 23152, (Mouse) 71722
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