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Invitrogen
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Immunogen sequence: PKRKMRRRSS CSSEPNTPKS AKCEGDIFTF DRTGTEAEDV LGELEYDKVP YSSLRRTLDQ RRALVMQLFQ DHGFFPSAQA TAAFQARYAD IFPSKVCLQL KIREVRQKIM QA
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Capicua; Protein capicua homolog
Gene Aliases: CIC; KIAA0306
UniProt ID: (Human) Q96RK0
Entrez Gene ID: (Human) 23152
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