Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
CIDEC Polyclonal Antibody
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
Product Details
PA1-4316
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues L(10) L Y P K S L S R H V S V R T S(25) of human CIDE-3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2079998
Product Specific Information
PA1-4316 detects the human CIDE-3 protein in human samples. Expected to recognize mouse samples due to 93% sequence homology.
PA1-4316 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~27 kDa protein representing human CIDE-3 in HepG2 cell lysate.
The PA1-4316 immunogen is a synthetic peptide corresponding to residues L(10) L Y P K S L S R H V S V R T S(25) of human CIDE-3. This antibody shows cross-reactivity to FSP27, which is the mouse homolog of CIDE-3, with a sequence identity of 93%.
Maintain at 4ºC for 3 months or at -20ºC for longer periods. Avoid repeated freeze-thaw cycles.
Target Information
DNA fragmentation is one of the critical steps in apoptosis, which is induced by DNA fragmentation factor (DFF). DFF is composed of two subunits, a 40 kDa caspase-activated nuclease (DFF40) and a 45 kDa inhibitor (DFF45). Recently a novel family of cell-death-inducing DFF45-like effectors (CIDEs) has been identified. Human CIDE-3 is a novel member of CIDEs. There are 2 transcripts, CIDE-3 and CIDE-3alpha, were present in HepG2 and A375 cells. Consistent with its chromosome localization at 3p25, a region associated with high frequency loss of heterozygosity in many tumours, CIDE-3 may play an important role in prevention of tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cell death activator CIDE-3; cell death-inducing DFFA-like effector c; Cell death-inducing DFFA-like effector protein C; CID; cide 3; CIDE-3alpha; fat specific gene 27; fat specific protein 27; Fat-specific protein FSP27; Fat-specific protein FSP27 homolog; Lipid transferase CIDEC
Gene Aliases: CIDE-3; CIDE3; CIDEC; FPLD5; FSP27
UniProt ID: (Human) Q96AQ7, (Mouse) P56198
Entrez Gene ID: (Human) 63924, (Mouse) 14311
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support