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Proteintech
CIRBP Polyclonal Antibody
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Product Details
10209-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat,
Rodent
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CIRBP Fusion Protein Ag0280 (1-172 aa encoded by BC000403)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody (10209-2-AP) is a rabbit polyclonal antibody raised against the full-length CIRBP of human origin.
Immunogen sequence: MASDEGKLF VGGLSFDTNE QSLEQVFSKY GQISEVVVVK DRETQRSRGF GFVTFENIDD AKDAMMAMNG KSVDGRQIRV DQAGKSSDNR SRGYRGGSAG GRGFFRGGRG RGRGFSRGGG DRGYGGNRFE SRSGGYGGSR DYYSSRSQSG GYSDRSSGGS YRDSYDSYAT HNE (1-172 aa encoded by BC000403)
Target Information
CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor and promotes assembly of stress granules (SGs), when overexpressed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A18 hnRNP; cold inducible RNA-binding protein; Cold-inducible RNA-binding protein; glycine-rich RNA binding protein; Glycine-rich RNA-binding protein CIRP; testicular tissue protein Li 39
Gene Aliases: A18HNRNP; CIRBP; CIRP; R74941
UniProt ID: (Human) Q14011, (Rat) P60825, (Mouse) P60824
Entrez Gene ID: (Human) 1153, (Rat) 81825, (Mouse) 12696
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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