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Bioss
CK 2 alpha Polyclonal Antibody
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FIGURE: 1 / 2
CK 2 alpha Antibody (BS-1607R) in WB
Lane 1: rat brain lysates Lane 2: rat heart lysates probed with Anti CK II alpha/STKPolyclonal Antibody, Unconjugated (bs-1607R) at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90 min in 37°C. Predicted band 43 kD. Observed band size: 43 kD.
Product Details
BS-1607R
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CK II alpha, amino acids 201-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; protein kinase CK2
Gene Aliases: CK2A1; CKII; Ckiia; CSNK2A1; Csnk2a1-rs4; CSNK2A3
UniProt ID: (Human) P68400, (Mouse) Q60737, (Rat) P19139
Entrez Gene ID: (Human) 1457, (Mouse) 12995, (Rat) 116549
protein phosphorylation
positive regulation of cell proliferation
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of protein catabolic process
protein autophosphorylation
regulation of catalytic activity
mitotic spindle checkpoint
regulation of cell growth
transcription, DNA-templated
regulation of transcription, DNA-templated
Wnt signaling pathway
regulation of cell proliferation
rhythmic process
protein folding
apoptotic process
signal transduction
chaperone-mediated protein folding
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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