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CK 2 beta Polyclonal Antibody
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Product Details
BS-2937R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CK II alpha beta, amino acids 151-215.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative name: G5a, phosvitin; casein kinase 2, beta polypeptide; casein kinase 2, beta subunit; Casein kinase II beta subunit; Casein kinase II subunit beta; chimera Csnk2b-Ly6g5b splicing isoform 2050; chimera Csnk2b-Ly6g5b splicing isoform 2275; chimera Csnk2b-Ly6g5b splicing isoform 2531; chimera Csnk2b-Ly6g5b splicing isoform 901; CK II beta; CSNK2B; Csnk2b splicing isoform 280; Csnk2b splicing isoform 662; Csnk2b-Ly6g5b; CSNK2B-LY6G5B-1072; CSNK2B-LY6G5B-1103; CSNK2B-LY6G5B-532; CSNK2B-LY6G5B-560; CSNK2B-LY6G5B-562; DADB-127H9.2; MGC138222; MGC138224; Phosvitin; Protein G5a; protein kinase; unnamed protein product
Gene Aliases: CK II beta; Ck2; CK2B; CK2N; Ckb1; Ckb2; CSK2B; CSNK2B; G5A; POBINDS
UniProt ID: (Human) P67870, (Rat) P67874, (Mouse) P67871
Entrez Gene ID: (Human) 1460, (Rat) 81650, (Mouse) 13001
chromatin binding
protein serine/threonine kinase activity
receptor binding
protein binding
protein kinase regulator activity
protein domain specific binding
protein binding, bridging
identical protein binding
metal ion binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
transcription factor binding
kinase modulator
signal transduction
negative regulation of cell proliferation
Wnt signaling pathway
peptidyl-threonine phosphorylation
release from viral latency
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of activin receptor signaling pathway
adiponectin-activated signaling pathway
negative regulation of blood vessel endothelial cell migration
positive regulation of SMAD protein import into nucleus
endothelial tube morphogenesis
protein-containing complex assembly
symbiont-mediated disruption of host cell PML body
negative regulation of viral life cycle
I-kappaB kinase/NF-kappaB signaling
positive regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of Wnt signaling pathway
regulation of protein kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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