Recommended positive controls: NT2D1, U87-MG.
Predicted reactivity: Mouse (87%), Rat (87%), Pig (87%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
CKAP1 binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cytoskeleton associated protein 1; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-folding cofactor B; Tubulin-specific chaperone B
Gene Aliases: CG22; CKAP1; CKAPI; TBCB
UniProt ID: (Human) Q99426
Entrez Gene ID: (Human) 1155
Molecular Function: chaperone