CKAP1 binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
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Protein Aliases: cytoskeleton associated protein 1; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; liver cancer related protein; Tubulin-folding cofactor B; Tubulin-specific chaperone B
Gene Aliases: 2410007D12Rik; AU041393; CG22; CKAP1; CKAPI; TBCB; ZH14
Molecular Function: chaperone