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IL-1F10 Monoclonal Antibody (5B2F5), CoraLite® Plus 488
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FIGURE: 1 / 1
IL-1F10 Antibody (CL488-60319) in Flow
1x10^6 U-937 cells were intracellularly stained with 0.4 µg CoraLite® Plus 488 Anti-Human IL-1F10 (CL488-60319, Clone: 5B2F5) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-60319
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5B2F5
Immunogen
IL-1F10 fusion protein Ag17250
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MCSLPMARY YIIKYADQKA LYTRDGQLLV GDPVADNCCA EKICTLPNRG LDRTKVPIFL GIQGGSRCLA CVETEEGPSL QLEDVNIEEL YKGGEEATRF TFFQSSSGSA FRLEAAAWPG WFLCGPAEPQ QPVQLTKESE PSARTKFYFE QSW
Target Information
The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection. IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil. IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses. IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Family of interleukin 1-theta; FIL1 theta; IL-1 theta; IL-1F10; IL-1F10 (canonical form IL-1F10a); IL-1HY2; IL-38; Interleukin; interleukin 1 family member 10 (theta); Interleukin-1 family member 10; Interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; Interleukin-1 theta; Interleukin-38
Gene Aliases: FIL1-theta; FIL1T; FKSG75; IL-1HY2; IL-38; IL1-theta; IL1F10; IL1HY2; IL38; UNQ6119/PRO20041
UniProt ID: (Human) Q8WWZ1
Entrez Gene ID: (Human) 84639
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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