Search
Proteintech
Sestrin 2 Monoclonal Antibody (1A1A4), CoraLite® Plus 488
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
CL488-66297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A1A4
Immunogen
Recombinant protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Purification
Protein G
Storage buffer
PBS with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: HMAEFLQTGG DPEWLLGLHR APEKLRKLSE INKLLAHRPW LITKEHIQAL LKTGEHTWSL AELIQALVLL THCHSLSSFV FGCGILPEGD ADGSPAPQAP TPPSEQSSPP SRDPLNNSGG FESARDVEAL MERMQQLQES LLRDEGTSQE EMESRFELEK SESLLVTPSA DILEPSPHPD MLCFVEDPTF GYEDFTRRGA QAPPTFRAQD YTWEDHGYSL IQRLYPEGGQ LLDEKFQAAY SLTYNTIAMH SGVDTSVLRR AIWNYIHCVF GIRYDDYDYG EVNQLLERNL KVYIKTVACY PEKTTRRMYN LFWRHFRHSE KVHVNLLLLE ARMQAALLYA LRAITRYMT
Target Information
This gene encodes a member of the sestrin family of PA26-related proteins. The encoded protein may function in the regulation of cell growth and survival. This protein may be involved in cellular response to different stress conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Hi95; hypoxia-responsive p53 target; hypoxia induced gene 95; hypoxia-induced; Hypoxia-induced gene; Sestrin-2; unnamed protein product
Gene Aliases: HI95; RGD1566319; SES2; SESN2; SEST2
UniProt ID: (Human) P58004
Entrez Gene ID: (Pig) 100620966, (Human) 83667, (Rat) 502988
regulation of protein phosphorylation
regulation of gluconeogenesis
fatty acid beta-oxidation
mitochondrion organization
response to glucose
positive regulation of macroautophagy
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
cellular response to nutrient levels
mitochondrial DNA metabolic process
response to insulin
cellular response to amino acid starvation
cellular response to oxidative stress
cellular response to glucose starvation
glucose homeostasis
glucose import
positive regulation of protein kinase B signaling
triglyceride homeostasis
protein K63-linked ubiquitination
cellular response to amino acid stimulus
cellular response to leucine
reactive oxygen species metabolic process
protein K6-linked ubiquitination
cellular oxidant detoxification
regulation of cAMP/PKA signal transduction
positive regulation of protein localization to nucleus
regulation of response to reactive oxygen species
negative regulation of translation in response to endoplasmic reticulum stress
regulation of TORC1 signaling
negative regulation of TORC1 signaling
positive regulation of TORC1 signaling
positive regulation of lipophagy
cellular response to leucine starvation
autophagy
protein kinase B signaling
regulation of gluconeogenesis involved in cellular glucose homeostasis
regulation of cAMP-dependent protein kinase activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support